Research Initiative for Scientific Enhancement
G-RISE T32GM148406
University of Puerto Rico, Medical Sciences Campus

Publications

Publications 2023-2024

Cruz-Collazo, A. M., Katsara, O., Grafals-Ruiz, N., Colon Gonzalez, J., Dorta-Estremera, S., Carlo, V. P., Chorna, N., Schneider, R. J., & Dharmawardhane, S. (2024). Novel Inhibition of Central Carbon Metabolism Pathways by Rac and CDC42 inhibitor MBQ167 and Paclitaxel. Molecular cancer therapeutics, 23(11), 1613–1625. https://doi.org/10.1158/1535-7163.MCT-23-0803.

 

Presentations of G-RISE Students

Student Name

Presentations at Conferences
Alanis P. Delgado- Suarez Title of Oral Presentation: “Neural Circuits and Motivation” 
Meeting: DataBlitz Presentation, BioCom Project
Place: UPR-School of Medicine
Date: Nov 1, 2023
Valeria C. Villarin- Ayala Title: Elucidating the role of apoptosis, ferroptosis and autophagy in ischemia- reperfusion injury in rat hearts
Meeting: XXI Simposio de Investigación Científica 2024
Place: Pontificia Universidad Católica de Puerto Rico, Recinto de Ponce
Date: April 26, 2024
Jessica Colon- Gonzalez Title of Poster Presentation: Screening of Rac-1 and Cdc42 inhibitors as anti- metastatic compounds. 
Meeting: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1.
Place: San Diego Convention Center, San Diego, California
Date: April 5-10, 2024

Title of Oral Presentation: Screening of Rac-1 and Cdc42 inhibitors as anti- metastatic compounds.
Meeting: 44th Annual Research and Education Forum of the UPR MSC.
Place: University of Puerto Rico Medical Sciences Campus
Date: March 13-15, 2024
Richard Mojica- Velez Title of Poster Presentation: Pharmacogenomic Study of Clopidogrel Response Using Genome-wide Association Tools in Caribbean Hispanics
Meeting: Pharmacogenomics Research Network Annual
Meeting Place: St. Jude Children Research Hospital at Memphis, Tennessee 
Date: June 12-13, 2023
Fabiola D. Pagan- Torres Title of Poster Presentation: Asymmetry of aggression is conserved in surface fish of the Mexican tetra independent of previous social experience
Meeting: 8th Astyanax International Meeting for Cavefish; Biennial meeting
Place: Fort Lauderdale, Florida, at the B Ocean Resort
Date: February 28 - March 2, 2024
Grecia Y. Geigel- Rodríguez Title of Poster Presentation: Continuous Flow-based Synthesis of Indomethacin from Biomass-derived Building Blocks.
Meeting: Mini Symposium – New Frontiers in Pharmaceutical Sciences: challenges and opportunities.
Place: University of Puerto Rico Medical Sciences Campus, Jaime Benitez Amphitheater
Date: January 26, 2024.

Title of Poster Presentation: Continuous Flow-based Synthesis of Indomethacin from Biomass-derived Building Blocks.
Meeting: 18th Belgian Organic Synthesis Symposium BOSS XVIII 2024.
Place: Liège, Belgium
Date: June 30 - July 5, 2024
Joseph Louis Capella Muniz Title of Poster Presentation: Intermittent Cocaine Self-Administration and Passive Infusions Increases Subthreshold Activity in Dopaminergic Neurons of the Ventral Tegmental Area
Meeting: 11th IBRO World Congress of Neuroscience 2023
Place: Granada, Spain
Authors: Calo-Guadalupe CG, Capella-Muñiz JL, Vélez-Acevedo O, Laboy-Juárez K, Bosque-Cordero KY, Jiménez-Rivera CA
Date: 9-13 September 2023.
Mitzy J. Santiago Rosario Title of Poster Presentation: Design and Synthesis of Novel NF-kB p50 Inhibitors from Andrographolide as a Potential Treatment for Prostate Cancer
Meeting: 38th National Medicinal Chemistry Symposium NMCS 2024
Place: Seattle, WA, United States
Date: June 23-26, 2024

Title of Poster Presentation: Synthesis of Andrographolide Derivatives as Potential Treatment for Prostate Cancer. Presented in two local events.
Meeting: G-RISE Mini Symposium – New Frontiers in Pharmaceutical Sciences: challenges and opportunities.
Place: University of Puerto Rico Medical Sciences Campus, Jaime Benitez Amphitheater
Date: January 26, 2024

Meeting: 44th Annual Research and Education Forum of the UPR MSC
Place: University of Puerto Rico Medical Sciences Campus,
Date: March 13-15, 2024
Kaitlyn Nieves Serra Title of Poster Presentation: Design and Synthesis of Novel TRIP13 Inhibitors for HPV-Driven Cancers
Authors: Kaitlyn Nieves Serra, BS, Jaelismarie Garcias Rivera, Soma Ghosh, PhD, Faye Johnson, PhD/MD, Cornelis P Vlaar, PhD 
Meeting: 38th ACS National Medicinal Chemistry Symposium
Place: Seattle, Washington
Date: June 23-26, 2024
Aleandra C. Ortiz Santiago Title of Poster Presentation: Development of Monocyte-Derived Microglia from HIV- Positive Patients to Study α7nAChR Therapeutic Potential against Neurocognitive Disorders
Meeting: Puerto Rico Neuroscience Conference
Authors: Aleandra C. Ortiz-Santiago, Lester J. Rosario-Rodríguez, Kamilis S. Hernández-Alejandro, Elaine Rodríguez & Valerie Wojna 
Place: UPR-Bayamon Campus, PR, USA
Date: December 2, 2023
Marie L Matos- Hernandez Title of Poster Presentation: Metabolomic Analysis and SARS-CoV-2 Antiviral Screening of a Marine Algae Extract Library Identify Jobosnoic Acid, a virus-selective Dual Inhibitor.
Authors: Marie L. Matos-Hernández, Robert Samples, Grayce Dyer, Victoria M. Casimir Montán, Chris A. Morales-Colón, Joseph M. Salvino, Luis J. Montaner, Joel A. Cassel, Troy E. Messick, Ian Tietjen, and Eduardo J.E. Caro-Diaz. 
Meeting: Gordon Research Conference and Seminar on Marine Natural Products
Place: Ventura, California
Date: March 10 - 15, 2024

Title: Antiviral Agents Derived from Marine Algae Natural Products
Authors: Marie L. Matos-Hernández
Meeting: Virtual Laboratory Meeting, Montaner’s Laboratory Research Group
Place: The Wistar Institute in Philadelphia, PA
Date: 2023 (Oral Presentation)
Victor G Reyes-Burgos Title of Poster Presentation: Targeting matrix metalloproteinase-3 (MMP-3) in high-grade serous ovarian cancer
Meeting: American Association for Cancer Research
Place: San Diego, California
Date: April 5-10, 2024

Title of Poster Presentation: Targeting matrix metalloproteinase-3 (MMP-3) in high- grade serous ovarian cancer
Meeting: University of Puerto Rico Medical Sciences Campus 44th Annual Research and Education Forum
Place: San Juan, PR
Date: March 13-15, 2024
Jose E Perez- Torres Title of Oral Presentation: The Role of Lateral Habenula in Approach-Avoidance Conflict
Meeting: Puerto Rico Physiological Society Annual Conference
Place: Ponce, PR
Date: February 23, 2024
Albersy Armina- Rodriguez Title of Poster Presentation: Fasciola hepatica recombinant FABP-Fh15, downregulates inflammatory cytokines while promoting survival in a mouse septic shock model
Meeting: Annual Meeting AAAS-Caribbean Division
Place: Casa Pueblo, Adjuntas, PR
Date: November 11, 2023

Title of Poster and Oral Presentation: The Anti-SARS-CoV-2 IgG1 and IgG3 Antibody Isotypes with Limited Neutralizing Capacity against Omicron Elicited in a Latin Population a Switch toward IgG4 after Multiple Doses with the mRNA Pfizer- BioNTech Vaccine
Meeting: Serological Sciences Network (SeroNet) Investigators Meeting
Place: The New York Academy of Medicine, New York, NY
Date: March 26-28, 2023.

Title of Poster Presentation: Recombinant Fasciola hepatica fatty acid binding protein, suppress key proteins of NF-κB and iNOS inflammatory pathways in in vitro stimulated cells with E. coli-LPS
Meeting: Annual Meeting of the American Association of Immunologists (AAI)
Place: Chicago, IL
Date: May 3-27, 2024
Grecia Y. Geigel- Rodríguez Title of Poster Presentation: Continuous Flow-based Synthesis of Indomethacin from Biomass-derived Building Blocks.
Meeting: Mini Symposium – New Frontiers in Pharmaceutical Sciences: challenges and opportunities.
Place: University of Puerto Rico Medical Sciences Campus, Jaime Benitez Amphitheater
Date: January 26, 2024.

Title of Poster Presentation: Continuous Flow-based Synthesis of Indomethacin from Biomass-derived Building Blocks.
Meeting: 18th Belgian Organic Synthesis Symposium BOSS XVIII 2024.
Place: Liège, Belgium
Date: June 30 - July 5, 2024
Joseph Louis Capella Muniz Title of Poster Presentation: Intermittent Cocaine Self-Administration and Passive Infusions Increases Subthreshold Activity in Dopaminergic Neurons of the Ventral Tegmental Area
Meeting: 11th IBRO World Congress of Neuroscience 2023
Place: Granada, Spain